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RFLP analysis of a large family indicated that one of the fr

Custom Essays biology RFLP analysis of a large family indicated that one of the fr

biology

RFLP analysis of a large family indicated that one of the fr

RFLP analysis of a large family indicated that one of the fragments on the gel fo rthe progeny below… Show more RFLP analysis of a large family indicated that one of the fragments on the gel fo rthe progeny below is tightly linked to a genetic disorder hairless. Which of the fragments may be used as a marker for the disorder? Is the RFLP marker fully linked to the phenotypic trait or not? Suggest genetic explanation for the inheritance of this disorder. Is it autosomal or sex-linked? Dominant or recessive? Phenotypes are as following(numbers from left to right): The RFLP fragments have 6 variants: 1,2,3,4,5,6 Parents: 1: 4,5 – normal female 2: 4,6 – hairless male 3: 1,2 – normal female 4: 3,4 – normal male F1: 5: 4,6 – hairless female 6: 1,3 – normal male F2: 7: 1,4 – normal female 8: 1,6 – hairless female 9: 3,4 – normal female 10:1,6 – hairless male 11: 3,6 – hairless male 12: 3,4 – normal female 13: 1,4 – normale male • Show less

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