Q3) Evidence (see P.G. Shiels, A.]. Kind, K.H. Campbell, et al. (1999). Analysis of telomere lengths… Show more Q3) Evidence (see P.G. Shiels, A.]. Kind, K.H. Campbell, et al. (1999). Analysis of telomere lengths in cloned sheep. Nature 399, 316-17) suggested that Dolly may have been “genetically older” than her actual age would have suggested. As mammals age, the chromosomes in somatic cells tend to shorten from the telomeres. Therefore, older individuals have shorter chromosomes in their somatic cells than do younger ones. When researchers analyzed the chromosomes in the somatic cells of Dolly when she was about 3 years old, the lengths of her chromosomes were consistent with a sheep that was significant ly older, say, 9 or 10 years old. (Note: As described in the chapter, the sheep that donated the somatic cell that produced Dolly was 6 years old, and her mammary cells had been grown in culture for several cell doublings before a mammary cell was fused with an oocyte.) A. Suggest an explanation why Dolly’s chromosomes seemed so old. B. Let’s suppose that Dolly at age 11 gave birth to a lamb named Molly; Molly was produced naturally (by mating Dolly with a normal male). When Molly was 8 years old, a sample of somatic cells was analyzed. How old would you expect Molly’s chromosomes to appear, based on the phenomenon of telomere shortening? Explain your answer. C. Discuss how the observation of chromosome shortening, which was observed in Dolly, might affect the popularity of reproductive cloning. • Show less