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There is a simple pedigree in which there are two normal par

Custom Essays biology There is a simple pedigree in which there are two normal par

biology

There is a simple pedigree in which there are two normal par

There is a simple pedigree in which there are two normal parents (phenotypically normal, but may be… Show more There is a simple pedigree in which there are two normal parents (phenotypically normal, but may be genetically abnormal) who have three offsprings, two of whom have died during the fetus stage. The surviving child (girl) is diagnosed with down syndrome. Her genetic karyotype shows that there was a translocation between the 21 chromome and 14 chromosome (it is not a robertsonian translocation) Question 1: What is the cause of the spontaneous abortion of the two children who died? Question 2: How would you explain the phenotypically normal parents but a child with down syndrome caused by translocation of chromosome 21 and 14 if it’s not a robertsonian translocation? Question 3: Are there any evolutionary significance? Question 4: Is it possible for the parents to have normal children in the future? • Show less

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